This study is being done to see if tucatinib with ado trastuzumab emtansine t dm1 works better than t dm1 alone to help patients who have a specific type of breast cancer called her2 positive breast carcinoma the breast cancer in this study is either metastatic spread into other parts of the body or cannot be removed completely with surgery patients in this study will be randomly assigned to get either tucatinib or placebo a pill with no medicine this is a blinded study so neither . Breast cancer is one of a few cancers for which an effective screening test mammography is available mri magnetic resonance imaging ultrasound and clinical breast exams are also used to detect breast cancer but not as routine screening tools ongoing studies are looking at ways to enhance current breast cancer screening options. Breast cancer cells are routinely tested for estrogen and progesterone receptors to help determine treatment options about 60 of breast cancer cells also have receptors for androgens male hormones initial studies in women with breast cancer show some response when using the antiandrogen bicalutamide to treat tnbc that has the androgen receptor bicalutamide is a drug that has been used to treat prostate cancer for many years more studies in breast cancer are ongoing. This section describes the research behind many of the recommendations and standards of practice related to breast cancer discussed in other sections research summary tables in our summary research tables you can see findings from many studies on topics including breast cancer risk factors screening treatment survivorship topics and social support research table topics how to read a
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